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  FEI Hao  费浩
  Division of Nanobiomedicine Research
  Peptide nanobiochemistry; Cell biology and microscopic imaging; Molecular bioconjugation;

Research Interest:

  1. Peptide based novel therapeutics development; 

  2. Cytotoxicity mechanisms of chemical & nanomaterials; 

  3. Functional probes for biosensing and bioimaging; 



  2008 -          Assoc. Prof.- Professor      Nanobiomedicine Division, SINANO, CAS 

  2005 - 2008    Assistant Researcher     UCLA, Los Angeles, CA 

  2001 - 2004      Postdoc. Research Fellow      Vollum Institute, OHSU, Portland, OR 


  Ph.D. 2001   Biochemistry and Molecular Biology        SIBCB, CAS 

  B.S.  1996   Biochemistry         Nanjing University 

Selected Publication:

  1.Liu X, Cao R, Wang S, Jia J, Fei H*. Amphipathicity determines different cytotoxic mechanisms of lysine- or arginine-rich cationic hydrophobic peptides in cancer cells. J. Med. Chem. 2016 May 19;  

  2.Wang Q, Ma X, Jia J, Fei H*. A peptide–lipid nanoparticle assembly platform with integrated functions for targeted cell delivery. J. Mater. Chem. B, 2016, 4, 1535 - 1543 

  3.Ma X, Jia J, Cao R, Wang X, Fei H*. Histidine–iridium(III) coordination-based peptide luminogenic cyclization and cyclo-RGD peptides for cancer-cell targeting. J. Am. Chem. Soc. 2014, 136 (51): 17734-17737. 

  4.Ma X, Wang X, Zhou M, Fei H*. A Mitochondria-Targeting Gold-Peptide Nanoassembly for Enhanced Cancer-Cell Killing. Adv Healthc Mater. 2013. Dec; 2(12):1638-43. 

  5.Cao R, Jia J, Ma X, Zhou M, Fei H*. Membrane localized iridium(III) complex induces endoplasmic reticulum stress and mitochondria-mediated apoptosis in human cancer cells. J. Med. Chem. 2013 May 9;56(9):3636-44. 

  6.Wang X, Jia J, Huang Z, Zhou M, Fei H*. Luminescent Peptide Labeling based on a Histidine-binding Iridium(III) Complex for Cell Penetration and Intracellular Targeting Studies.  Chemistry – A European Journal. 2011 Jul 11;17(29): 8028-32. 

  7.Fei H, Karnezis T, Reimer RJ, Krantz DE: Membrane topology of Drosophila vesicular glutamate transporter. J. Neurochem. 2007 Jun;101(6):1662-71. 

  8.Scott GK, Fei H, Thomas L, Megideshi G, Thomas G: PACS-1, GGA3 and CK2 cooperate to control CI-MPR trafficking. EMBO J. 2006 Oct 4;25(19):4423-35. 

  9.Fei H, Luo MJ, Ye YZ, Ding DF, Chi CW: The Inhibitory Activities of Recombinant Eglin C Mutants on Kexin and Furin, Using Site-directed Mutagenesis and Molecular Modeling.  Acta Biochimica et Biophysica Sinica. 2001;33(6):591-599.